SCHEMBL338055

SCHEMBL338055

O=c1ccn(CO)c(=O)[nH]1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
LMNA P02545 1/20 0.56
PKM P14618 1/20 0.51
CRBN Q96SW2 3/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
DUT P33316 8/20 0.46
DDB1 Q16531 1/20 0.44
ENPP1 P22413 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2983407 0.83 ALDH1A1 (0.57) ALDH1A1LMNAPKMCRBNL3MBTL1
SCHEMBL10924758 0.82 PKM (0.55) ALDH1A1LMNAPKMCRBNL3MBTL1
SCHEMBL4348697 0.82 L3MBTL1 (0.59) ALDH1A1LMNAPKMCRBNL3MBTL1
SCHEMBL4347791 0.81 ALDH1A1 (0.50) ALDH1A1LMNAPKMCRBNL3MBTL1
SCHEMBL3079985 0.80 DUT (0.56) ALDH1A1LMNACRBNL3MBTL1DUT
SCHEMBL6102943 0.80 CRBN (0.56) ALDH1A1LMNAPKMCRBNL3MBTL1
SCHEMBL5180752 0.79 ALDH1A1 (0.49) ALDH1A1LMNAPKMCRBNL3MBTL1
SCHEMBL913206 0.79 DUT (0.55) ALDH1A1LMNAL3MBTL1DUT
SCHEMBL254514 0.79 DUT (0.56) ALDH1A1LMNAPKML3MBTL1DUT
SCHEMBL8377765 0.78 PKM (0.51) ALDH1A1LMNAPKMCRBNL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 500 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137486-A1 CAP COMPOUNDS AND RNAS COMPRISING THE SAME HELIX NANOTECHNOLOGIES INC (US) 2025-06-26 WO claimed
US-20250206770-A1 CAP COMPOUNDS AND RNAS COMPRISING THE SAME HELIX NANOTECHNOLOGIES INC 2025-06-26 US claimed
EP-4337331-A1 MODIFIED MRNA, MODIFIED NON-CODING RNA, AND USES THEREOF The Broad Institute Inc. (US) 2024-03-20 EP claimed
EP-4314332-A2 METHODS FOR IDENTIFICATION AND RATIO DETERMINATION OF RNA SPECIES IN MULTIVALENT RNA COMPOSITIONS ModernaTX, Inc. (US) 2024-02-07 EP claimed
CN-109804083-B Single primer to double primer amplicon conversion 西格马-奥尔德里奇有限责任公司 2023-11-03 CN claimed
EP-4133111-A1 DEVICE AND METHOD FOR PHOTOTHERMAL ENHANCED PLASMONIC BIOSENSING EMPA Eidgenössische Materialprüfungs- und Forschungsanstalt (CH) 2023-02-15 EP claimed
US-20220315972-A1 SINGLE PRIMER TO DUAL PRIMER AMPLICON SWITCHING SIGMA ALDRICH CO LLC (US) 2022-10-06 US claimed
US-11400042-B2 Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone L'OREAL (FR) 2022-08-02 US claimed
US-11390913-B2 Single primer to dual primer amplicon switching SIGMA-ALDRICH CO. LLC (US) 2022-07-19 US claimed
US-11298305-B2 Compositions and methods for improving the appearance of the hair L'OREAL (FR) 2022-04-12 US claimed
WO-2016183100-A1 COMPOSITIONS AND METHODS FOR NUCLEIC ACID AMPLIFICATION Twist Bioscience Corporation (US) 2016-11-17 WO claimed
US-20150093752-A1 Conversion of alpha-hydroxyalkylated residues in biomolecules using methyltransferases VILNIUS UNIVERSITY (LT) 2015-04-02 US claimed
WO-2008033432-A2 IMMUNE MODULATION BY CHEMICALLY MODIFIED RIBONUCLEOSIDES AND OLIGORIBONUCLEOTIDES COLEY PHARMACEUTICAL GROUP, INC. (US) 2008-03-20 WO claimed
EP-1282639-A2 POLYAMIDE NUCLEIC ACID DERIVATIVES, AGENTS AND METHODS FOR PRODUCING THE SAME Aventis Pharma Deutschland GmbH (DE) 2003-02-12 EP claimed
WO-2001079249-A2 PEPTIDE NUCLEIC ACID DERIVATIVES WITH A NEGATIVE CHARGE, AGENTS AND METHODS FOR PRODUCING THEM AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-10-25 WO claimed
WO-2001068807-A2 IDENTIFICATION OF IN VIVO DNA BINDING LOCI OF CHROMATIN PROTEINS USING A TETHERED NUCLEOTIDE MODIFICATION ENZYME FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2001-09-20 WO claimed
EP-0934521-A1 IN VITRO ASSAY FOR CARCINOGENS USING PHENOTYPIC TRANSFORMATION OF HUMAN CELLS Viratest Carcinogen Monitoring, Ltd. (CA) 1999-08-11 EP claimed
US-5763180-A In vitro assay for carcinogens using phenotypic transformation of human cells VIRATEST CARCINOGEN MONITORING LTD. (CA) 1998-06-09 US claimed
WO-1998007030-A1 IN VITRO ASSAY FOR CARCINOGENS USING PHENOTYPIC TRANSFORMATION OF HUMAN CELLS VIRATEST CARCINOGEN MONITORING LTD. (US) 1998-02-19 WO claimed
WO-1993017651-A2 ANTIVIRAL NUCLEOSIDE ANALOGUES, THEIR PRODUCTION AND USE Max-Delbrück-Centrum für Molekulare Medizin (DE) 1993-09-16 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11298305-B2 Compositions and methods for improving the appearance of the hair KRT18, OAT, CKMT1A; CKMT1B ALDH1A1 2800/4885LMNA 1081/4885PKM 889/4885
US-20250206770-A1 CAP COMPOUNDS AND RNAS COMPRISING THE SAME RNGTT, RNMT, NSUN2 ALDH1A1 1939/4885LMNA 828/4885PKM 4358/4885
US-11400042-B2 Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone KRT18, CUTA, PUF60 ALDH1A1 3876/4885LMNA 477/4885PKM 264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.