Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 5/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isofezolac SCHEMBL25481 | 0.78 | ALDH1A1 (0.52) | ALDH1A1PTGS1PTGS2LMNAALOX5 | |
| Ibuproxam SCHEMBL24896 | 0.73 | CHRM1 (1.00) | CHRM1PDE4AMAPK1CXCR1CXCR2 | |
| Ibuproxam SCHEMBL10428212 | 0.73 | CHRM1 (1.00) | CHRM1PDE4AMAPK1CXCR1CXCR2 | |
| Ibuproxam SCHEMBL8722617 | 0.73 | CHRM1 (1.00) | CHRM1PDE4AMAPK1CXCR1CXCR2 | |
| SCHEMBL11731137 | 0.72 | MEN1 (0.41) | ALDH1A1RAB9ALMNAALOX5 | |
| SCHEMBL13013589 | 0.71 | POLB (0.58) | ALDH1A1RAB9ALMNACYP2C9 | |
| Oxaprozin SCHEMBL28086540 | 0.70 | RXRA (0.61) | CHRM1PDE4AMAPK1PTGS1PTGS2 | |
| Ibuproxam SCHEMBL28086418 | 0.70 | CHRM1 (0.88) | CHRM1PDE4AMAPK1CXCR1CXCR2 | |
| SCHEMBL11729083 | 0.70 | NR3C1 (0.43) | ALDH1A1NPSR1ALOX5AKR1C2 | |
| Isofezolac SCHEMBL5967922 | 0.70 | NPC1 (0.64) | RAB9ALMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137371-A1 | Novel Pharmaceutical Compounds | MERCK FROSST CANADA LTD. (CA) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137371-A1 | Novel Pharmaceutical Compounds | LTC4S, LTA4H, LTB4R2 | CHRM1 1843/4885PDE4A 862/4885ALDH1A1 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.