Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856234 | 0.72 | ALOX15 (0.40) | MEN1KMT2AALDH1A1NNMT | |
| SCHEMBL29856260 | 0.70 | SLC22A12 (0.41) | MEN1KMT2ACYP1A2CYP3A4HPGD | |
| SCHEMBL29856346 | 0.68 | DYRK1A (0.34) | ACSS2CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL1149532 | 0.67 | MAT2A (0.39) | ERN1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL1348764 | 0.65 | ALDH1A1 (0.41) | MEN1NPC1RAB9AKMT2AGABRP | |
| SCHEMBL29856264 | 0.65 | MAPT (0.39) | CRHR1ACSS2MAPTNNMT | |
| SCHEMBL16943001 | 0.63 | LMNA (0.30) | HTTMAPT | |
| SCHEMBL29856981 | 0.63 | ERN1 (0.39) | ERN1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL16093663 | 0.63 | DYRK1A (0.52) | MEN1KMT2AGSK3BHPGDHTT | |
| SCHEMBL12435903 | 0.62 | MAPT (0.40) | MEN1KMT2AGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |