Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.30 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856229 | 0.73 | ALOX15 (0.39) | CYP3A4HPGD | |
| SCHEMBL29857005 | 0.69 | SLC22A12 (0.43) | CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL22863572 | 0.69 | ALDH1A1 (0.46) | DYRK1AMAOABCHEACHEDDB1 | |
| SCHEMBL29856253 | 0.68 | ERN1 (0.35) | ACSS2CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL441518 | 0.65 | ERN1 (0.37) | MAOA | |
| SCHEMBL746493 | 0.65 | ERN1 (0.44) | — | |
| SCHEMBL29954802 | 0.65 | ERN1 (0.37) | MAOA | |
| SCHEMBL29856468 | 0.64 | ACSS2 (0.38) | DYRK1AMAOABCHEACHEACSS2 | |
| SCHEMBL25230147 | 0.63 | ERN1 (0.36) | CYP3A4CYP2C19 | |
| SCHEMBL772591 | 0.63 | ERN1 (0.46) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |