Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24016459 | 0.83 | MTNR1A (0.56) | ATAD2DAOMAPTHRH4PRMT5 | |
| SCHEMBL12677225 | 0.81 | ATAD2 (0.53) | ATAD2PKMDAOMAPTSNCA | |
| SCHEMBL29865073 | 0.79 | PKM (0.39) | PKMMAPTCYP2A6NPC1RAB9A | |
| SCHEMBL27144888 | 0.78 | DAO (0.48) | ATAD2DAOHRH4NR3C1PRMT5 | |
| SCHEMBL9396748 | 0.77 | DAO (0.53) | ATAD2PKMDAOMAPTSNCA | |
| SCHEMBL30040118 | 0.77 | DAO (0.53) | ATAD2PKMDAOMAPTSNCA | |
| SCHEMBL2175546 | 0.77 | LOXL2 (0.52) | ATAD2PKMDAOMAPTSNCA | |
| SCHEMBL27658755 | 0.77 | DAO (0.49) | ATAD2PKMDAOMAPTSNCA | |
| SCHEMBL4862801 | 0.77 | DAO (0.49) | ATAD2PKMDAOMAPTSNCA | |
| SCHEMBL25587553 | 0.77 | DAO (0.43) | ATAD2DAOMAPTHRH4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022175425-A1 | INHALED MTOR KINASE INHIBITORS FOR USE IN THE TREATMENT OR THE PREVENTION OF A RESPIRATORY RNA VIRUS INFECTION | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-08-25 | — | — | WO | claimed |