Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.39 |
| ▸ | CBFB | Q13951 | 6/20 | 0.36 |
| ▸ | METAP2 | P50579 | 5/20 | 0.36 |
| ▸ | METAP1 | P53582 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 7/20 | 0.35 |
| ▸ | RAB9A | P51151 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29865238 | 0.79 | ATAD2 (0.49) | PKMMETAP2METAP1NPC1RAB9A | |
| SCHEMBL29525714 | 0.76 | CBFB (0.41) | PKMCBFBMETAP2METAP1NPC1 | |
| SCHEMBL21964305 | 0.75 | NOS1 (0.41) | PKM | |
| SCHEMBL29864204 | 0.68 | TYRO3 (0.39) | PKMSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1460651 | 0.65 | LOXL2 (0.58) | — | |
| SCHEMBL24016459 | 0.65 | MTNR1A (0.56) | KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL29525433 | 0.64 | PSMD14 (0.41) | PKMMETAP2METAP1NPC1RAB9A | |
| SCHEMBL23493049 | 0.64 | CYP2A6 (0.46) | CYP2A6MAPT | |
| SCHEMBL21964304 | 0.64 | BCHE (0.42) | SMN1; SMN2LMNA | |
| SCHEMBL548491 | 0.63 | F10 (0.43) | PKMNPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022175425-A1 | INHALED MTOR KINASE INHIBITORS FOR USE IN THE TREATMENT OR THE PREVENTION OF A RESPIRATORY RNA VIRUS INFECTION | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-08-25 | — | — | WO | claimed |