[18F]Fluspidine

[18F]Fluspidine

SCHEMBL29873189

[17F]CCC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SLC18A3 Q16572 2/20 1.00
▸ EBPL Q9BY08 1/20 1.00
▸ SIGMAR1 Q99720 5/20 0.78
▸ OPRM1 P35372 4/20 0.78
▸ OPRK1 P41145 4/20 0.78
▸ EBP Q15125 3/20 0.78
▸ OPRD1 P41143 2/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2360466 0.80 SIGMAR1 (0.72) SLC18A3EBPLSIGMAR1OPRM1OPRK1
SCHEMBL2360468 0.80 SIGMAR1 (0.72) SLC18A3EBPLSIGMAR1OPRM1OPRK1
SCHEMBL3403111 0.80 SIGMAR1 (0.72) SLC18A3EBPLSIGMAR1OPRM1OPRK1
SCHEMBL11684907 0.79 SIGMAR1 (0.70) SLC18A3EBPLSIGMAR1OPRM1OPRK1
SCHEMBL25357939 0.77 SIGMAR1 (1.00) SLC18A3EBPLSIGMAR1OPRM1OPRK1
SCHEMBL25358487 0.77 SIGMAR1 (1.00) SLC18A3EBPLSIGMAR1OPRM1OPRK1
SCHEMBL25358883 0.77 SIGMAR1 (0.74) SLC18A3EBPLSIGMAR1OPRM1OPRK1
SCHEMBL11736902 0.74 SIGMAR1 (0.63) SLC18A3EBPLSIGMAR1OPRM1OPRK1
Hydrochloric Acid SCHEMBL11733052 0.73 SIGMAR1 (0.62) SLC18A3EBPLSIGMAR1OPRM1OPRK1
SCHEMBL25358545 0.72 SIGMAR1 (0.70) SLC18A3EBPLSIGMAR1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12514937-B2 Methods for detecting CCR2 receptors WASHINGTON UNIVERSITY (US) 2026-01-06 — — US claimed
US-12036213-B2 Pridopidine for treating drug induced dyskinesias PRILENIA NEUROTHERAPEUTICS LTD. (IL) 2024-07-16 — — US disclosed
US-20240216553-A1 DEVELOPMENT OF CD163 TARGETING AGENT FOR IMAGING AND THERAPY WASHINGTON UNIVERSITY 2024-07-04 — — US disclosed
US-20230112948-A1 USE OF PRIDOPIDINE FOR TREATING ANXIETY AND DEPRESSION PRILENIA NEUROTHERAPEUTICS LTD. (IL) 2023-04-13 — — US disclosed
US-11471449-B2 Use of pridopidine to improve cognitive function and for treating Alzheimer's disease PRILENIA NEUROTHERAPEUTICS LTD. (IL) 2022-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12036213-B2 Pridopidine for treating drug induced dyskinesias SLC6A3, QDPR, PARK7 SLC18A3 41/4885EBPL 4415/4885SIGMAR1 1492/4885
US-20230112948-A1 USE OF PRIDOPIDINE FOR TREATING ANXIETY AND DEPRESSION DRD2, DRD4, HTR5A SLC18A3 143/4885EBPL 3833/4885SIGMAR1 669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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