Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20670355 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KMT2APOLBKDM4ETP53 | |
| SCHEMBL22519435 | 0.80 | CHRM5 (0.40) | ALDH1A1KMT2AKDM4ECYP1A2TDP1 | |
| SCHEMBL29889219 | 0.79 | ALDH1A1 (0.44) | ALDH1A1OPRM1 | |
| SCHEMBL20670356 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KMT2APOLBKDM4EOPRM1 | |
| SCHEMBL18936836 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KMT2ASLC22A1SLC6A4ADRA1A | |
| SCHEMBL29889214 | 0.78 | CYP2C19 (0.43) | ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL27685278 | 0.78 | BDKRB2 (0.38) | KMT2ASLC22A1SLC6A4ADRA1AOPRM1 | |
| SCHEMBL10280046 | 0.78 | L3MBTL1 (0.33) | ALDH1A1KMT2ASLC22A1SLC6A4ADRA1A | |
| SCHEMBL1095665 | 0.78 | KMT2A (0.42) | ALDH1A1KMT2ASLC22A1SLC6A4ADRA1A | |
| SCHEMBL25447273 | 0.77 | CYP2C19 (0.36) | KMT2ATP53SLC22A1SLC6A4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306674-A1 | (2-ACETAMIDYL)THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306674-A1 | (2-ACETAMIDYL)THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES | LGALS1, LGALS3, LGALS2 | ALDH1A1 255/4885KMT2A 3636/4885POLB 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.