Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22234018 | 0.88 | KIF11 (0.52) | S1PR1S1PR3DPP4KIF11HRH4 | |
| SCHEMBL5217538 | 0.88 | S1PR1 (0.51) | S1PR1S1PR3DPP4KIF11HRH4 | |
| SCHEMBL28071862 | 0.83 | ADORA2A (0.59) | DPP4KIF11HRH4LMNATHRB | |
| SCHEMBL28879162 | 0.83 | ADORA3 (0.52) | S1PR1S1PR3DPP4KIF11LMNA | |
| SCHEMBL8031410 | 0.80 | LMNA (0.62) | S1PR1S1PR3DPP4KIF11HRH4 | |
| SCHEMBL5672174 | 0.79 | HTT (0.46) | HRH4LMNAADORA2AADORA1NPC1 | |
| SCHEMBL7228785 | 0.78 | KIF11 (0.52) | S1PR1S1PR3DPP4KIF11LMNA | |
| SCHEMBL3898550 | 0.78 | ADORA2A (0.72) | DPP4KIF11LMNAADORA3ADORA2A | |
| SCHEMBL3156245 | 0.77 | ADORA2A (0.66) | DPP4LMNAADORA3ADORA2AADORA1 | |
| SCHEMBL3898780 | 0.76 | ADORA2A (0.51) | DPP4KIF11HRH4LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |