Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15130503 | 1.00 | ALOX15 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL322219 | 1.00 | ALOX15 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL5981375 | 1.00 | ALOX15 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL15130505 | 1.00 | ALOX15 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL19501942 | 1.00 | ALOX15 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6469073 | 0.98 | USP2 (0.56) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6469069 | 0.98 | USP2 (0.56) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL12375142 | 0.87 | USP2 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL1577675 | 0.87 | USP2 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL751609 | 0.87 | USP2 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207282-A1 | METHOD OF INCREASING CHAPERONE MEDIATED AUTOPHAGY BY STABILIZING THE INTERACTION OF RETINOIC ACID RECEPTOR-ALPHA AND AN INHIBITOR | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2024-06-27 | — | — | US | disclosed |
| US-20240189307-A1 | METHODS OF STABILIZING THE NEURONAL PROTEOME AGAINST COLLAPSE AND PROTECTING VASCULAR CELLS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2024-06-13 | — | — | US | disclosed |
| EP-4326267-A1 | METHOD OF INCREASING CHAPERONE MEDIATED AUTOPHAGY BY STABILIZING THE INTERACTION OF RETINOIC ACID RECEPTOR-ALPHA AND AN INHIBITOR | Albert Einstein College of Medicine (US) | 2024-02-28 | — | — | EP | disclosed |
| EP-4326396-A1 | METHODS OF STABILIZING THE NEURONAL PROTEOME AGAINST COLLAPSE AND PROTECTING VASCULAR CELLS | Albert Einstein College of Medicine (US) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022226191-A9 | METHODS OF STABILIZING THE NEURONAL PROTEOME AGAINST COLLAPSE AND PROTECTING VASCULAR CELLS | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2023-11-30 | — | — | WO | disclosed |
| CN-112094259-B | Iodine (III) -mediated radiofluorination | 通用医疗公司 | 2023-09-01 | — | — | CN | disclosed |
| US-11707538-B2 | Methods and devices to generate [F-18]triflyl fluoride and other [F-18] sulfonyl fluorides | WASHINGTON UNIVERSITY (US) | 2023-07-25 | — | — | US | disclosed |
| WO-2022226187-A1 | METHOD OF INCREASING CHAPERONE MEDIATED AUTOPHAGY BY STABILIZING THE INTERACTION OF RETINOIC ACID RECEPTOR-ALPHA AND AN INHIBITOR | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022226191-A1 | METHODS OF STABILIZING THE NEURONAL PROTEOME AGAINST COLLAPSE AND PROTECTING VASCULAR CELLS | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2022-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240189307-A1 | METHODS OF STABILIZING THE NEURONAL PROTEOME AGAINST COLLAPSE AND PROTECTING VASCULAR CELLS | CTSA, SNCA, HTT | ALOX15 2326/4885HSD17B10 4303/4885USP2 185/4885 |
| US-11707538-B2 | Methods and devices to generate [F-18]triflyl fluoride and other [F-18] sulfonyl fluorides | STX18, PFAS, FLI1 | ALOX15 4529/4885HSD17B10 2884/4885USP2 2425/4885 |
| US-20240207282-A1 | METHOD OF INCREASING CHAPERONE MEDIATED AUTOPHAGY BY STABILIZING THE INTERACTION OF RETINOIC ACID RECEPTOR-ALPHA AND AN INHIBITOR | NCOR1, NCOR2, RARA | ALOX15 2028/4885HSD17B10 1765/4885USP2 1496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.