O-Xylene

O-Xylene

SCHEMBL2990079

Cc1ccccc1C.O=S(=O)(O)C(F)(F)F

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.48
TSHR P16473 2/20 0.48
HSD11B1 P28845 3/20 0.42
TRPA1 O75762 2/20 0.41
ATM Q13315 1/20 0.41
PTPN1 P18031 1/20 0.39
PDK1 Q15118 1/20 0.38
PDK2 Q15119 1/20 0.38
PDK3 Q15120 1/20 0.38
PDK4 Q16654 1/20 0.38
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ABCC9 O60706 1/20 0.36
ABCC8 Q09428 1/20 0.36
KCNJ11 Q14654 1/20 0.36
KCNJ8 Q15842 1/20 0.36
SDHB P21912 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL27876773 0.98 ACHE (0.46) ACHETSHRHSD11B1TRPA1ATM
Orthocresol SCHEMBL28383837 0.89 TRPA1 (0.46) ACHETSHRHSD11B1TRPA1ATM
O-Tolylamine SCHEMBL5161740 0.86 CYP3A4 (0.56) TSHRHSD11B1TRPA1ATMPTPN1
Trifluoromethanesulfonic Acid SCHEMBL30038181 0.86 MAPT (0.40) ACHETSHRHSD11B1TRPA1ATM
Trifluoromethanesulfonic Acid SCHEMBL28564485 0.85 TRPA1 (0.52) TSHRHSD11B1TRPA1ATMPTPN1
Trifluoromethanesulfonic Acid SCHEMBL28746827 0.84 HSD11B1 (0.36) ACHETSHRHSD11B1TRPA1ATM
Trifluoromethanesulfonic Acid SCHEMBL180454 0.84 TSHR (0.50) ACHETSHRHSD11B1PTPN1SMN1; SMN2
Trifluoromethanesulfonic Acid SCHEMBL27943511 0.82 ALDH1A1 (0.40) TSHRHSD11B1PDK2SMN1; SMN2CA2
Trifluoromethanesulfonic Acid SCHEMBL6423662 0.82 ALDH1A1 (0.40) TSHRHSD11B1PDK2SMN1; SMN2CA2
Trifluoromethanesulfonic Acid SCHEMBL23877542 0.82 TSHR (0.48) ACHETSHRHSD11B1PTPN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140011097-A1 TERT-BUTYLPHENYL SULFONATE COMPOUND, NONAQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY USING THE SAME, AND LITHIUM SECONDARY BATTERY USING THE SAME UBE INDUSTRIES, LTD. (JP) 2014-01-09 US disclosed
US-8546599-B2 Tert-butylphenyl sulfonate compound, nonaqueous electrolyte solution for lithium secondary battery using the same, and lithium secondary battery using the same UBE INDUSTRIES, LTD. (JP) 2013-10-01 US disclosed
US-20100055576-A1 tert-BUTYLPHENYL SULFONATE COMPOUND, NONAQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY USING THE SAME, AND LITHIUM SECONDARY BATTERY USING THE SAME MU IONIC SOLUTIONS CORPORATION (JP) 2010-03-04 US disclosed
EP-2133327-A1 tert-BUTYLPHENYL SULFONATE COMPOUND, NONAQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY USING THE SAME, AND LITHIUM SECONDARY BATTERY USING THE SAME Ube Industries, Ltd. (JP) 2009-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100055576-A1 tert-BUTYLPHENYL SULFONATE COMPOUND, NONAQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY USING THE SAME, AND LITHIUM SECONDARY BATTERY USING THE SAME TERT, TST, TES ACHE 1240/4885TSHR 760/4885HSD11B1 2744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.