SCHEMBL3419749

SCHEMBL3419749

COc1c(C)ccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 6/20 0.70
▸ RAB9A P51151 5/20 0.70
▸ NPC1 O15118 3/20 0.70
▸ ALDH1A1 P00352 7/20 0.59
▸ CYP3A4 P08684 4/20 0.59
▸ ELANE P08246 3/20 0.59
▸ MAPK1 P28482 3/20 0.59
▸ TSHR P16473 2/20 0.59
▸ CASP3 P42574 1/20 0.59
▸ HBB P68871 1/20 0.59
▸ SENP7 Q9BQF6 1/20 0.59
▸ SENP6 Q9GZR1 1/20 0.59
▸ L3MBTL1 Q9Y468 1/20 0.59
▸ MAPT P10636 8/20 0.54
▸ MEN1 O00255 4/20 0.54
▸ KMT2A Q03164 4/20 0.54
▸ KDM4E B2RXH2 4/20 0.52
▸ TDP1 Q9NUW8 2/20 0.52
▸ USP2 O75604 1/20 0.52
▸ DUSP3 P51452 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28527666 0.83 SMN1; SMN2 (0.56) SMN1; SMN2RAB9ANPC1ALDH1A1CYP3A4
SCHEMBL1426442 0.82 SMN1; SMN2 (0.70) SMN1; SMN2RAB9ANPC1ALDH1A1CYP3A4
SCHEMBL29906115 0.82 SMN1; SMN2 (0.70) SMN1; SMN2RAB9ANPC1ALDH1A1CYP3A4
SCHEMBL496978 0.82 RAB9A (1.00) SMN1; SMN2RAB9ANPC1ALDH1A1CYP3A4
SCHEMBL3182071 0.81 RAB9A (0.58) SMN1; SMN2RAB9ANPC1ALDH1A1CYP3A4
SCHEMBL28783594 0.79 EPHX2 (0.53) SMN1; SMN2RAB9ANPC1ALDH1A1CYP3A4
SCHEMBL29669840 0.79 EPHX2 (0.53) SMN1; SMN2RAB9ANPC1ALDH1A1CYP3A4
SCHEMBL769353 0.79 ALDH1A1 (0.75) SMN1; SMN2RAB9ANPC1ALDH1A1CYP3A4
SCHEMBL57336 0.77 ALDH1A1 (0.67) SMN1; SMN2RAB9ANPC1ALDH1A1CYP3A4
SCHEMBL29501107 0.77 ALDH1A1 (0.67) SMN1; SMN2RAB9ANPC1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3943085-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2022-01-26 — — EP claimed
US-20210186947-A1 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH ZURICH (CH) 2021-06-24 — — US claimed
EP-3801507-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2021-04-14 — — EP claimed
US-20250346721-A1 FOAM COMPOSITION INCLUDING SILICONE MQ RESINS AND RELATED ARTICLES AND PROCESSES 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-11-13 — — US disclosed
EP-4532593-A1 FOAM COMPOSITION INCLUDING SILICONE MQ RESINS AND RELATED ARTICLES AND PROCESSES 3M Innovative Properties Company (US) 2025-04-09 — — EP disclosed
CN-119421918-A Foam compositions comprising surface-modified nanoparticles and related articles and methods 3M创新有限公司 2025-02-11 — — CN disclosed
CN-119301185-A Foam compositions comprising silicone MQ resins and related articles and methods 3M创新有限公司 2025-01-10 — — CN disclosed
CN-116057143-B Double-sided tissue tape and related articles 3M创新有限公司 2024-12-13 — — CN disclosed
CN-117836384-A Single layer adhesive film and related articles 3M创新有限公司 2024-04-05 — — CN disclosed
WO-2023233379-A1 FOAM COMPOSITION INCLUDING SILICONE MQ RESINS AND RELATED ARTICLES AND PROCESSES 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-12-07 — — WO disclosed
WO-2023233376-A1 FOAM COMPOSITION INCLUDING SURFACE-MODIFIED NANOPARTICLES AND RELATED ARTICLES AND PROCESSES 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-12-07 — — WO disclosed
US-20150152298-A1 PRESSURE-SENSITIVE ADHESIVES WITH MIXED PHOTOCROSSLINKING SYSTEM 3M INNOVATIVE PROPERTIES COMPANY 2015-06-04 — — US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 — — US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 — — US disclosed
US-8980967-B2 Pressure-sensitive adhesives with mixed photocrosslinking system 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-03-17 — — US disclosed
EP-2702080-A1 PRESSURE-SENSITIVE ADHESIVES WITH MIXED PHOTOCROSSLINKING SYSTEM 3M Innovative Properties Company (US) 2014-03-05 — — EP disclosed
US-20140039083-A1 PRESSURE-SENSITIVE ADHESIVES WITH MIXED PHOTOCROSSLINKING SYSTEM 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-02-06 — — US disclosed
WO-2012148608-A1 PRESSURE-SENSITIVE ADHESIVES WITH MIXED PHOTOCROSSLINKING SYSTEM 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-11-01 — — WO disclosed
US-20100129723-A1 NON-AQUEOUS ELECTROLYTE FOR PRIMARY BATTERY, AND NON-AQUEOUS ELECTROLYTE PRIMARY BATTERY USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2010-05-27 — — US disclosed
EP-1933404-A1 NON-AQUEOUS ELECTROLYTE FOR PRIMARY BATTERY, AND NON-AQUEOUS ELECTROLYTE PRIMARY BATTERY USING THE SAME Mitsubishi Chemical Corporation (JP) 2008-06-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210186947-A1 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION TOMM70, TOMM34, TIMM50 SMN1; SMN2 4118/4885RAB9A 3373/4885NPC1 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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