Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG4B | Q9Y4P1 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18529295 | 0.77 | ATG4B (1.00) | ATG4B | |
| SCHEMBL29908348 | 0.77 | RAB9A (0.69) | ATG4BLMNAROCK2ROCK1GAA | |
| SCHEMBL6799629 | 0.72 | MAPT (0.56) | LMNAMAPK1KMT2ANPC1MAPT | |
| SCHEMBL8778065 | 0.71 | LMNA (0.52) | ATG4BLMNAMAPK1KMT2ANPC1 | |
| SCHEMBL14434568 | 0.71 | LMNA (0.73) | LMNANAMPTROCK2EPHX2KMT2A | |
| SCHEMBL3656623 | 0.71 | ROCK2 (0.62) | ATG4BLMNANAMPTROCK2ROCK1 | |
| SCHEMBL29128699 | 0.71 | MEN1 (0.50) | LMNAMAPK1KMT2ANPC1MAPT | |
| SCHEMBL5795303 | 0.70 | MGMT (0.57) | KMT2ANPC1MAPTRAB9A | |
| SCHEMBL29128667 | 0.70 | LMNA (0.50) | LMNAMAPK1KMT2ANPC1MAPT | |
| SCHEMBL9687003 | 0.70 | LMNA (0.54) | LMNAMAPK1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188203-A1 | IMIDAZOPYRIDINE DERIVATIVE | 北京富龙康泰生物技术有限公司 | 2022-09-15 | — | — | WO | disclosed |