Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735125 | 0.76 | MAPT (1.00) | MAPTMEN1KMT2AGAANPC1 | |
| SCHEMBL5635894 | 0.75 | MAPT (0.53) | MAPTMEN1KMT2AGAANPC1 | |
| SCHEMBL9339801 | 0.75 | MAPT (0.56) | MAPTMEN1KMT2AGAANPC1 | |
| SCHEMBL4353311 | 0.74 | DPYD (0.50) | MAPTGAALMNAALDH1A1TSHR | |
| SCHEMBL600199 | 0.72 | NPSR1 (0.55) | MAPTMEN1KMT2AGAANPC1 | |
| SCHEMBL2534548 | 0.71 | MAPT (0.65) | MAPTMEN1KMT2AGAANPC1 | |
| SCHEMBL5635893 | 0.71 | MAPT (0.51) | MAPTMEN1KMT2AGAANPC1 | |
| SCHEMBL6699936 | 0.70 | GLS (0.71) | MAPTNPC1RAB9ATDP1CASP3 | |
| SCHEMBL2535334 | 0.70 | GAA (0.73) | MAPTMEN1KMT2AGAANPC1 | |
| SCHEMBL650217 | 0.70 | MAPT (0.86) | MAPTMEN1KMT2AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7777024-B2 | Process for preparing a pentopyranosyl nucleic acid conjugate | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. (DE) | 2010-08-17 | — | — | US | disclosed |
| US-20090221793-A1 | PROCESS FOR PREPARING A PENTOPYRANOSYL NUCLEIC ACID CONJUGATE | SANOFI-AVENTIS S.A. (FR) | 2009-09-03 | — | — | US | disclosed |
| US-7501506-B2 | Pentopyranosyl nucleic acid conjugates | NANOGEN RECOGNOMICS GMBH (DE) | 2009-03-10 | — | — | US | disclosed |
| US-7153955-B2 | Pentopyranosyl nucleic acid arrays, and uses thereof | NANOGEN RECOGNOMICS GMBH (DE) | 2006-12-26 | — | — | US | disclosed |
| US-20060270840-A1 | Pentopyranosyl nucleic acid conjugates | SANOFI-AVENTIS S.A. (FR) | 2006-11-30 | — | — | US | disclosed |
| EP-1034180-B1 | LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | NANOGEN RECOGNOMICS GMBH (DE) | 2006-03-29 | — | — | EP | disclosed |
| US-20050053945-A1 | Process for the preparation of a pentopyranosyl conjugate | NANOGEN RECOGNOMICS GMBH | 2005-03-10 | — | — | US | disclosed |
| US-20050004356-A1 | Linker nucleoside, its preparation and use | NANOGEN RECOGNOMICS GMBH (DE) | 2005-01-06 | — | — | US | disclosed |
| US-20040198966-A1 | Pentopyranosylnucleoside, its preparation and use | NANOGEN RECOGNOMICS GMBH | 2004-10-07 | — | — | US | disclosed |
| EP-1017703-B1 | PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | NANOGEN RECOGNOMICS GMBH (DE) | 2004-04-28 | — | — | EP | disclosed |
| US-6608186-B1 | Of given formula; use for the production of a therapeutic, diagnostic and/or electronic component; use in the construction of supramolecular units | NANOGEN RECOGNOMICS GMBH (DE) | 2003-08-19 | — | — | US | disclosed |
| US-20030039997-A1 | Pentopyranosyl nucleic acid arrays, and uses thereof | AVENTIS RESEARCH AND TECHNOLOGIES GMBH & CO. KG (DE) | 2003-02-27 | — | — | US | disclosed |
| EP-1019423-B1 | METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE | NANOGEN RECOGNOMICS GMBH (DE) | 2003-02-26 | — | — | EP | disclosed |
| US-6506896-B1 | Conjugated to peptides, proteins, nucleic acids, antibodies, RNA, or DNA; medical diagnosis, electronics | NANOGEN RECOGNOMICS GMBH (DE) | 2003-01-14 | — | — | US | disclosed |
| EP-1034180-A2 | LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | Nanogen Recognomics GmbH (DE) | 2000-09-13 | — | — | EP | disclosed |
| EP-1019423-A2 | METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE | Nanogen Recognomics GmbH (DE) | 2000-07-19 | — | — | EP | disclosed |
| EP-1017703-A2 | PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | Nanogen Recognomics GmbH (DE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015540-A2 | METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1999-04-01 | — | — | WO | disclosed |
| WO-1999015542-A2 | LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-01 | — | — | WO | disclosed |
| WO-1999015539-A2 | PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221793-A1 | PROCESS FOR PREPARING A PENTOPYRANOSYL NUCLEIC ACID CONJUGATE | RNGTT, NT5C3B, FUT6 | MAPT 4293/4885MEN1 2365/4885KMT2A 2433/4885 |
| US-20040198966-A1 | Pentopyranosylnucleoside, its preparation and use | FUT6, ST3GAL3, FUT5 | MAPT 2753/4885MEN1 891/4885KMT2A 4304/4885 |
| US-20050004356-A1 | Linker nucleoside, its preparation and use | RNGTT, NSUN2, NSUN3 | MAPT 2837/4885MEN1 3656/4885KMT2A 2254/4885 |
| US-20050053945-A1 | Process for the preparation of a pentopyranosyl conjugate | FUT6, FUT5, FUCA2 | MAPT 2338/4885MEN1 874/4885KMT2A 3591/4885 |
| US-20060270840-A1 | Pentopyranosyl nucleic acid conjugates | FUT6, RNGTT, B3GAT3 | MAPT 4091/4885MEN1 3055/4885KMT2A 2501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.