Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.50 |
| ▸ | DHODH | Q02127 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | EEF2K | O00418 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL2991025 | 1.00 | PDE10A (0.50) | PDE10ADHODHLMNATSHRKMT2A | |
| SCHEMBL9056825 | 0.88 | PDE10A (0.54) | PDE10ADHODHLMNATSHRKMT2A | |
| SCHEMBL9056820 | 0.88 | PDE10A (0.54) | PDE10ADHODHLMNATSHRKMT2A | |
| SCHEMBL641899 | 0.84 | PDE10A (0.66) | PDE10ADHODHLMNATSHRKMT2A | |
| SCHEMBL29377848 | 0.84 | PDE10A (0.66) | PDE10ADHODHLMNATSHRKMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL6014201 | 0.83 | MEN1 (0.56) | PDE10ADHODHKMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL1603404 | 0.82 | PDE10A (0.63) | PDE10ADHODHLMNATSHRKMT2A | |
| Iodide SCHEMBL8029606 | 0.82 | PDE10A (0.63) | PDE10ADHODHLMNATSHRKMT2A | |
| Phenazine SCHEMBL30542151 | 0.82 | MAPT (0.50) | KMT2AALDH1A1MEN1KDM4EGLA | |
| Iodide SCHEMBL8029601 | 0.82 | PDE10A (0.63) | PDE10ADHODHLMNATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9533974-B2 | Ultra-sensitive chemiluminescent substrates for enzymes and their conjugates | MICHIGAN DIAGNOSTICS, LLC (US) | 2017-01-03 | — | — | US | disclosed |
| US-20150031889-A1 | ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | GIRI BRIJ PAL (US) | 2015-01-29 | — | — | US | disclosed |
| US-8932881-B2 | Ultra-sensitive chemiluminescent substrates for enzymes and their conjugates | GIRI BRIJ PAL (US) | 2015-01-13 | — | — | US | disclosed |
| US-20140088297-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | MICHIGAN DIAGNOSTICS, LLC (US) | 2014-03-27 | — | — | US | disclosed |
| US-20140073771-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | MICHIGAN DIAGNOSTICS, LLC (US) | 2014-03-13 | — | — | US | disclosed |
| US-7781229-B2 | water-soluble, stable in aqueous buffers, for use in biological assaying include acridane-based compounds and (1,2)-dioxetanes; used in the detection of antibodies or antigen in biological fluids and for compounds, particularly toxins and contaminants in the environment and food. | MICHIGAN DIAGNOSTICS, LLC (US) | 2010-08-24 | — | — | US | disclosed |
| US-20070225498-A1 | water-soluble, stable in aqueous buffers, for use in biological assaying include acridane-based compounds and (1,2)-dioxetanes; used in the detection of antibodies or antigen in biological fluids and for compounds, particularly toxins and contaminants in the environment and food. | MICHIGAN DIAGNOSTICS, LLC | 2007-09-27 | — | — | US | disclosed |
| EP-1735621-A2 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | Giri, Brij P. (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2006073424-A9 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | GIRI BRIJ P (US) | 2006-08-24 | — | — | WO | disclosed |
| WO-2006073424-A2 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | GIRI BRIJ P (US) | 2006-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088297-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | DUOX1, XDH, MPO | PDE10A 977/4885DHODH 106/4885LMNA 2129/4885 |
| US-20150031889-A1 | ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | DUOX1, XDH, MPO | PDE10A 986/4885DHODH 116/4885LMNA 1938/4885 |
| US-20070225498-A1 | water-soluble, stable in aqueous buffers, for use in biological assaying include acridane-based compounds and (1,2)-dioxetanes; used in the detection of antibodies or antigen in biological fluids and for compounds, particularly toxins and contaminants in the environment and food. | BTD, DDT, LPO | PDE10A 1849/4885DHODH 157/4885LMNA 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.