Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995773 | 0.96 | ALDH1A1 (0.46) | SIGMAR1CNR2LMNAALDH1A1MAPT | |
| SCHEMBL3005711 | 0.96 | LMNA (0.43) | SIGMAR1CNR2LMNAALDH1A1MAPT | |
| SCHEMBL2998712 | 0.95 | ALDH1A1 (0.47) | SIGMAR1CNR2LMNAALDH1A1MAPT | |
| SCHEMBL3008409 | 0.94 | L3MBTL1 (0.43) | SIGMAR1CNR2LMNAALDH1A1MAPT | |
| SCHEMBL2995185 | 0.93 | CNR2 (0.41) | SIGMAR1CNR2LMNAALDH1A1MAPT | |
| SCHEMBL3001380 | 0.92 | LMNA (0.48) | SIGMAR1LMNAALDH1A1MAPTALOX12 | |
| SCHEMBL4378256 | 0.91 | LMNA (0.45) | SIGMAR1CNR2LMNAALDH1A1MAPT | |
| SCHEMBL3005888 | 0.91 | PLA2G2A (0.47) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3002533 | 0.90 | MAPT (0.43) | SIGMAR1CNR2LMNAALDH1A1MAPT | |
| SCHEMBL2992509 | 0.90 | L3MBTL1 (0.42) | SIGMAR1CNR2LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197708-A1 | INDOLE COMPOUNDS | WELLS FARGO BANK, NATIONAL ASSOCIATION | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197708-A1 | INDOLE COMPOUNDS | IDO1, IDO2, TPH2 | SIGMAR1 547/4885CNR2 20/4885LMNA 3450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.