Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24774081 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2MAPK1PRMT1 | |
| SCHEMBL29922149 | 0.69 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL24774791 | 0.69 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL8859782 | 0.65 | ALDH1A1 (0.82) | KDM4EALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL757747 | 0.65 | KDM4E (0.82) | KDM4EALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL3483987 | 0.65 | MGLL (0.42) | KDM4EALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL52405 | 0.63 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL29366129 | 0.63 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL836635 | 0.62 | PGR (0.36) | KDM4EMAPTLMNAPOLBMEN1 | |
| Iodide SCHEMBL5967814 | 0.61 | ALDH1A1 (0.94) | KDM4EALDH1A1SMN1; SMN2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4054560-A1 | RIG-I INNATE IMMUNE RECEPTOR ANTAGONISTS AND METHODS OF USING SAME | Yale University (US) | 2022-09-14 | — | — | EP | disclosed |