Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ULK1 | O75385 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | CCR8 | P51685 | 2/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916494 | 1.00 | NQO2 (0.37) | NQO2TNKSMAPTNPC1RAB9A | |
| SCHEMBL24915600 | 0.78 | P2RX3 (0.40) | TNKSMAPTMEN1KMT2A | |
| SCHEMBL17502532 | 0.77 | NSD2 (0.40) | CCR1CCR5CCR8RIPK2KDR | |
| SCHEMBL29923616 | 0.71 | MTNR1B (0.49) | NQO2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL425260 | 0.71 | MTNR1B (0.49) | NQO2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL29376192 | 0.70 | ALDH1A1 (0.38) | MAPTCRHR1CCR1CCR5CCR8 | |
| SCHEMBL16105558 | 0.70 | ALDH1A1 (0.38) | MAPTCRHR1CCR1CCR5CCR8 | |
| SCHEMBL24715886 | 0.70 | NQO2 (0.47) | NQO2MAPTNPC1RAB9ACCR1 | |
| SCHEMBL19783646 | 0.69 | ALDH1A1 (0.40) | NQO2MAPTNPC1RAB9ACRHR1 | |
| SCHEMBL29923835 | 0.69 | MAPT (0.45) | MAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |