Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.48 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946268 | 0.86 | TASP1 (0.51) | TASP1GNPATALDH1A1PTPN1BACE1 | |
| SCHEMBL29664764 | 0.84 | TASP1 (0.56) | TASP1GNPATALDH1A1PTPN1MME | |
| SCHEMBL29881733 | 0.81 | TASP1 (0.44) | TASP1ALDH1A1MMEEDNRACASP1 | |
| SCHEMBL29802264 | 0.81 | TASP1 (0.51) | TASP1PTPN1BACE1CTSDCASP1 | |
| SCHEMBL24616790 | 0.80 | TASP1 (0.48) | TASP1GNPATPTPN1 | |
| SCHEMBL14035809 | 0.80 | GNPAT (0.46) | TASP1GNPATALDH1A1PTPN1MME | |
| SCHEMBL3866137 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MMP8CAPN1 | |
| SCHEMBL9542347 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MMP8CAPN1 | |
| SCHEMBL7510270 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MMP8CAPN1 | |
| SCHEMBL5493312 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240415928-A1 | LA PROTEIN AS A NOVEL REGULATOR OF OSTEOCLASTOGENESIS | THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-12-19 | — | — | US | disclosed |
| WO-2024197320-A2 | TARGETING SF3B2 FOR AXONAL PROTECTION IN CENTRAL NERVOUS SYSTEM NEURODEGENERATIVE DISEASES | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-09-26 | — | — | WO | disclosed |
| WO-2024192340-A2 | TARGETING SF3B2 FOR AXONAL PROTECTION IN CENTRAL NERVOUS SYSTEM NEURODEGENERATIVE DISEASES | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-09-19 | — | — | WO | disclosed |
| US-20240041978-A1 | LA PROTEIN AS A NOVEL REGULATOR OF OSTEOCLASTOGENESIS | THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-02-08 | — | — | US | disclosed |
| EP-4301396-A1 | LA PROTIEN AS A NOVEL REGULATOR OF OSTEOCLASTOGENESIS | The United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2024-01-10 | — | — | EP | disclosed |
| WO-2022187440-A1 | LA PROTIEN AS A NOVEL REGULATOR OF OSTEOCLASTOGENESIS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2022-09-09 | — | — | WO | disclosed |