SCHEMBL29664764

SCHEMBL29664764

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nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TASP1 Q9H6P5 1/20 0.56
▸ PTPN1 P18031 1/20 0.43
▸ KEAP1 Q14145 1/20 0.42
▸ MME P08473 2/20 0.41
▸ GNPAT O15228 1/20 0.41
▸ FOLH1 Q04609 3/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ BACE1 P56817 1/20 0.38
▸ BACE2 Q9Y5Z0 1/20 0.38
▸ CTNNB1 P35222 1/20 0.38
▸ BMP1 P13497 2/20 0.37
▸ GRIN2D O15399 1/20 0.37
▸ GRIN3B O60391 1/20 0.37
▸ GRIN1 Q05586 1/20 0.37
▸ GRIN2A Q12879 1/20 0.37
▸ GRIN2B Q13224 1/20 0.37
▸ GRIN2C Q14957 1/20 0.37
▸ GRIN3A Q8TCU5 1/20 0.37
▸ CASP1 P29466 1/20 0.36
▸ CASP3 P42574 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29946268 0.94 TASP1 (0.51) TASP1PTPN1GNPATFOLH1ALDH1A1
SCHEMBL14035809 0.88 GNPAT (0.46) TASP1PTPN1MMEGNPATFOLH1
SCHEMBL29802264 0.88 TASP1 (0.51) TASP1PTPN1BACE1BACE2CASP1
SCHEMBL24616790 0.85 TASP1 (0.48) TASP1PTPN1KEAP1GNPATBMP1
SCHEMBL23133286 0.84 TASP1 (0.43) TASP1PTPN1GNPATBACE1BACE2
SCHEMBL23133168 0.84 TASP1 (0.43) TASP1PTPN1GNPATBACE1BACE2
SCHEMBL1499722 0.84 TASP1 (0.43) TASP1PTPN1GNPATBACE1BACE2
SCHEMBL29923992 0.84 TASP1 (0.48) TASP1PTPN1MMEGNPATALDH1A1
SCHEMBL4100803 0.83 CASP1 (0.50) TASP1GNPATBACE1BACE2BMP1
SCHEMBL13194679 0.83 CASP1 (0.50) TASP1GNPATBACE1BACE2BMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022123062-A1 BLOCKING CASPASE AND/OR FASL FOR PREVENTING FATAL OUTCOME IN COVID-19 PATIENTS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-06-16 — — WO claimed
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-05-08 — — US disclosed
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-04-17 — — US disclosed
US-12139744-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2024-11-12 — — US disclosed
US-12110533-B2 Stabilisation and isolation of extracellular nucleic acids QIAGEN GMBH (DE) 2024-10-08 — — US disclosed
EP-4397770-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PreAnalytiX GmbH (CH) 2024-07-10 — — EP disclosed
EP-3401406-B1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PREANALYTIX GMBH (CH) 2023-11-29 — — EP disclosed
US-11525155-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2022-12-13 — — US disclosed
US-20220364149-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2022-11-17 — — US disclosed
WO-2022123062-A1 BLOCKING CASPASE AND/OR FASL FOR PREVENTING FATAL OUTCOME IN COVID-19 PATIENTS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-06-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 TASP1 4313/4885PTPN1 3212/4885KEAP1 4373/4885
US-12139744-B2 Stabilisation of biological samples RNASE1, RNASEH1, EWSR1 TASP1 4313/4885PTPN1 3212/4885KEAP1 4373/4885
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 TASP1 4313/4885PTPN1 3212/4885KEAP1 4373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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