Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 2/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CPA2 | P48052 | 1/20 | 0.38 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946268 | 0.91 | TASP1 (0.51) | GNPATPTPN1TASP1FOLH1ALDH1A1 | |
| SCHEMBL16131673 | 0.89 | FOLH1 (0.42) | PTPN1TASP1FOLH1BMP1CAPN1 | |
| SCHEMBL29664764 | 0.88 | TASP1 (0.56) | GNPATPTPN1TASP1FOLH1ALDH1A1 | |
| SCHEMBL29802264 | 0.85 | TASP1 (0.51) | PTPN1TASP1CASP1CASP3CASP7 | |
| SCHEMBL4100803 | 0.84 | CASP1 (0.50) | GNPATTASP1BMP1CASP1CASP3 | |
| SCHEMBL29310042 | 0.84 | CASP1 (0.50) | GNPATTASP1BMP1CASP1CASP3 | |
| SCHEMBL1674857 | 0.84 | CASP1 (0.50) | GNPATTASP1BMP1CASP1CASP3 | |
| SCHEMBL13194679 | 0.84 | CASP1 (0.50) | GNPATTASP1BMP1CASP1CASP3 | |
| SCHEMBL14008770 | 0.84 | ALDH1A1 (0.63) | GNPATPTPN1FOLH1ALDH1A1BMP1 | |
| SCHEMBL7510270 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CAPN1CPA1CPA2CPA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280937-A1 | Ligand Conjugates of Vinca Alkaloids, Analogs, and Derivatives | ENDOCYTE, INC. | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280937-A1 | Ligand Conjugates of Vinca Alkaloids, Analogs, and Derivatives | VDR, HCAR1, FOLR1 | GNPAT 2212/4885PTPN1 4771/4885TASP1 2754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.