SCHEMBL29946268

SCHEMBL29946268

CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C=O)CC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TASP1 Q9H6P5 1/20 0.51
▸ FOLH1 Q04609 9/20 0.45
▸ ALDH1A1 P00352 1/20 0.44
▸ PTPN1 P18031 1/20 0.44
▸ GNPAT O15228 1/20 0.42
▸ BMP1 P13497 2/20 0.40
▸ CASP1 P29466 1/20 0.39
▸ BACE1 P56817 1/20 0.39
▸ BACE2 Q9Y5Z0 1/20 0.39
▸ CTNNB1 P35222 1/20 0.38
▸ MMP3 P08254 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29664764 0.94 TASP1 (0.56) TASP1FOLH1ALDH1A1PTPN1GNPAT
SCHEMBL29802264 0.93 TASP1 (0.51) TASP1PTPN1CASP1BACE1BACE2
SCHEMBL14035809 0.91 GNPAT (0.46) TASP1FOLH1ALDH1A1PTPN1GNPAT
SCHEMBL29923992 0.86 TASP1 (0.48) TASP1ALDH1A1PTPN1GNPATCASP1
SCHEMBL13194679 0.85 CASP1 (0.50) TASP1GNPATBMP1CASP1BACE1
SCHEMBL1674857 0.85 CASP1 (0.50) TASP1GNPATBMP1CASP1BACE1
SCHEMBL4100803 0.85 CASP1 (0.50) TASP1GNPATBMP1CASP1BACE1
SCHEMBL29310042 0.85 CASP1 (0.50) TASP1GNPATBMP1CASP1BACE1
SCHEMBL10068454 0.85 CASP1 (0.47) TASP1GNPATCASP1BACE1BACE2
SCHEMBL29432579 0.84 REN (0.51) TASP1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-05-08 — — US disclosed
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-04-17 — — US disclosed
US-12139744-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2024-11-12 — — US disclosed
US-12110533-B2 Stabilisation and isolation of extracellular nucleic acids QIAGEN GMBH (DE) 2024-10-08 — — US disclosed
EP-4397770-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PreAnalytiX GmbH (CH) 2024-07-10 — — EP disclosed
EP-3401406-B1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PREANALYTIX GMBH (CH) 2023-11-29 — — EP disclosed
US-11525155-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2022-12-13 — — US disclosed
US-20220364149-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2022-11-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 TASP1 4313/4885FOLH1 1594/4885ALDH1A1 3862/4885
US-12139744-B2 Stabilisation of biological samples RNASE1, RNASEH1, EWSR1 TASP1 4313/4885FOLH1 1594/4885ALDH1A1 3862/4885
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 TASP1 4313/4885FOLH1 1594/4885ALDH1A1 3862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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