SCHEMBL29924649 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	LMNA	P02545	4/20	0.39

▸	TBXA2R	P21731	1/20	0.36

▸	MEN1	O00255	1/20	0.36

▸	KMT2A	Q03164	1/20	0.36

▸	ENPP2	Q13822	6/20	0.36

▸	MAPT	P10636	2/20	0.36

▸	TP53	P04637	3/20	0.35

▸	PDE4A	P27815	1/20	0.34

▸	PDE4B	Q07343	1/20	0.34

▸	PDE4C	Q08493	1/20	0.34

▸	PDE4D	Q08499	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29555183	0.80	MEN1 (0.55)	LMNAMEN1KMT2AMAPTTP53
SCHEMBL9635804	0.72	LMNA (0.47)	LMNATBXA2RMEN1KMT2AENPP2
SCHEMBL4772386	0.72	TP53 (0.51)	LMNATBXA2RMEN1KMT2AENPP2
SCHEMBL30497261	0.71	MEN1 (0.43)	MEN1KMT2ATP53
SCHEMBL29111000	0.70	LMNA (0.40)	LMNATBXA2RMEN1KMT2AENPP2
SCHEMBL29491420	0.70	LMNA (0.40)	LMNATBXA2RMEN1KMT2AENPP2
SCHEMBL9634894	0.68	SLC6A9 (0.53)	LMNATBXA2RMEN1KMT2AENPP2
SCHEMBL9635952	0.68	LMNA (0.45)	LMNATBXA2RMEN1KMT2AENPP2
SCHEMBL16768160	0.67	GAA (0.51)	LMNAMEN1KMT2AMAPTTP53
SCHEMBL6881772	0.66	DRD4 (0.48)	LMNAMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022228490-A1	POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF	上海翰森生物医药科技有限公司	2022-11-03	—	—	WO	disclosed