Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | KCNK13 | Q9HB14 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634927 | 0.80 | CHRM5 (0.50) | LMNATLR7MEN1KMT2A | |
| SCHEMBL4988044 | 0.73 | LMNA (0.43) | LMNAENPP2TBXA2RTP53MEN1 | |
| SCHEMBL4772386 | 0.73 | TP53 (0.51) | LMNAENPP2TBXA2RTP53MEN1 | |
| SCHEMBL9635804 | 0.73 | LMNA (0.47) | LMNAENPP2TBXA2RTP53MEN1 | |
| SCHEMBL9540969 | 0.72 | LMNA (0.46) | LMNAENPP2TBXA2RTP53MEN1 | |
| SCHEMBL6881772 | 0.72 | DRD4 (0.48) | LMNATP53MAPT | |
| SCHEMBL29643806 | 0.71 | MTNR1A (0.44) | GABRA1GABRA5KCNK13 | |
| SCHEMBL29491420 | 0.68 | LMNA (0.40) | LMNAENPP2TBXA2RTP53MEN1 | |
| SCHEMBL29111000 | 0.68 | LMNA (0.40) | LMNAENPP2TBXA2RTP53MEN1 | |
| SCHEMBL9634894 | 0.68 | SLC6A9 (0.53) | LMNAENPP2TBXA2RTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086056-A | Treating allergic diseases | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-04 | — | — | US | disclosed |
| US-5011842-A | Antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-04-30 | — | — | US | disclosed |
| US-4946843-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-08-07 | — | — | US | disclosed |