Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CISD2 | Q8N5K1 | 2/20 | 0.42 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27101661 | 0.75 | CYP46A1 (0.47) | SMN1; SMN2CYP46A1ALDH1A1TDP1KDM4E | |
| SCHEMBL29936733 | 0.74 | CNR2 (0.54) | KMT2AMEN1MAPK1CISD2ALDH1A1 | |
| SCHEMBL29936962 | 0.74 | MAPT (0.48) | KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL522175 | 0.72 | TSHR (0.61) | KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL29936713 | 0.71 | HSD17B1 (0.41) | KMT2AMEN1GFERSMN1; SMN2MAPK1 | |
| SCHEMBL2832514 | 0.70 | L3MBTL1 (0.51) | KMT2AMEN1GFERSMN1; SMN2MAPK1 | |
| SCHEMBL26571944 | 0.70 | TDP1 (0.61) | ALPLKMT2AMEN1SMN1; SMN2CYP46A1 | |
| SCHEMBL1719721 | 0.70 | TSHR (0.59) | SMN1; SMN2MAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL6838053 | 0.70 | BDKRB1 (0.50) | CYP46A1HSD17B10 | |
| SCHEMBL29936444 | 0.70 | ALDH1A1 (0.50) | ALPLKMT2AMEN1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010600-B | Method for synthesizing polyfluoroaryl carboxylic acid compound based on aryl fluorocarbon bond carboxylation reaction | 四川大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-115010600-A | Method for synthesizing polyfluoroaryl carboxylic acid compounds based on aryl fluorocarbon bond carboxylation reaction | 四川大学 | 2022-09-06 | — | — | CN | disclosed |