Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | NPM1 | P06748 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946004 | 0.85 | CTSB (0.39) | ALKSLC6A2SLC6A4SLC6A3JAK2 | |
| SCHEMBL29945820 | 0.79 | MAPT (0.46) | KMT2ASMN1; SMN2 | |
| SCHEMBL29945894 | 0.78 | INPPL1 (0.46) | INPPL1INSRNPM1ALKSLC6A2 | |
| SCHEMBL29946030 | 0.76 | MEN1 (0.41) | INPPL1SLC6A2SLC6A4SLC6A3CXCR3 | |
| SCHEMBL29946064 | 0.71 | INPPL1 (0.46) | INPPL1ALKSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28086989 | 0.67 | FPR2 (0.48) | SLC6A2SLC6A4SLC6A3CXCR3FPR2 | |
| SCHEMBL29946026 | 0.67 | SMN1; SMN2 (0.38) | KMT2AIDO1RAB9ASMN1; SMN2 | |
| SCHEMBL29946002 | 0.66 | HTR6 (0.49) | INPPL1INSRNPM1ALKSLC6A2 | |
| SCHEMBL8152659 | 0.65 | KMT2A (0.57) | KMT2AIDO1RAB9ASMN1; SMN2 | |
| Bromide SCHEMBL3173149 | 0.64 | KMT2A (0.56) | KMT2AIDO1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |