Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
| ▸ | NPM1 | P06748 | 1/20 | 0.37 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945894 | 0.89 | INPPL1 (0.46) | HTR6ALKSLC6A4HTR2AHTR2C | |
| SCHEMBL29945912 | 0.87 | KDM1A (0.39) | HTR6ALKSLC6A4MAP4K3SLC6A2 | |
| SCHEMBL29946041 | 0.79 | GPR119 (0.45) | — | |
| SCHEMBL29946008 | 0.76 | INPPL1 (0.43) | ALKSLC6A4MAP4K3SLC6A2SLC6A3 | |
| SCHEMBL24265554 | 0.75 | MAP4K3 (0.48) | SLC6A4HTR2CMAP4K3SLC6A2SLC6A3 | |
| SCHEMBL29946021 | 0.75 | INPPL1 (0.43) | MAP4K3INPPL1SIGMAR1 | |
| SCHEMBL14635365 | 0.74 | SIGMAR1 (0.43) | ALKHTR2AHTR2CINSRNPM1 | |
| SCHEMBL29946073 | 0.74 | MAP4K3 (0.49) | HTR6SLC6A4MAP4K3SLC6A2SLC6A3 | |
| SCHEMBL29945931 | 0.73 | MAP4K3 (0.50) | HTR6SLC6A4HTR2CMAP4K3SLC6A2 | |
| SCHEMBL24485665 | 0.72 | HTR6 (0.54) | HTR6SLC6A4SLC6A2SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |