Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 1/20 | 0.46 |
| ▸ | MAP4K3 | Q8IVH8 | 5/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | NPM1 | P06748 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946002 | 0.89 | HTR6 (0.49) | INPPL1MAP4K3JAK2ALKINSR | |
| SCHEMBL29945912 | 0.85 | KDM1A (0.39) | MAP4K3JAK2ALKHTR6SLC6A4 | |
| SCHEMBL29946021 | 0.84 | INPPL1 (0.43) | INPPL1MAP4K3 | |
| SCHEMBL29946064 | 0.82 | INPPL1 (0.46) | INPPL1MAP4K3JAK2ALKMCHR1 | |
| SCHEMBL29945931 | 0.81 | MAP4K3 (0.50) | INPPL1MAP4K3MCHR1HTR6SLC6A4 | |
| SCHEMBL29945877 | 0.80 | GPR119 (0.43) | — | |
| SCHEMBL29946008 | 0.79 | INPPL1 (0.43) | INPPL1MAP4K3ALKSLC6A4SLC6A2 | |
| SCHEMBL29946013 | 0.78 | MAP4K3 (0.39) | INPPL1MAP4K3JAK2ALKINSR | |
| SCHEMBL29945844 | 0.78 | INPPL1 (0.37) | INPPL1MAP4K3JAK2ALKINSR | |
| SCHEMBL30583851 | 0.76 | HTR6 (0.45) | MCHR1HTR6SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |