Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 4/20 | 0.35 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946008 | 0.88 | INPPL1 (0.43) | KDM1ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL29946002 | 0.87 | HTR6 (0.49) | SLC6A2SLC6A4SLC6A3HTR6JAK2 | |
| SCHEMBL29945894 | 0.85 | INPPL1 (0.46) | SLC6A2SLC6A4SLC6A3HTR6KCNH2 | |
| SCHEMBL24266549 | 0.83 | HTR6 (0.41) | KDM1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL29945954 | 0.82 | KDM1A (0.40) | KDM1ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL24265672 | 0.82 | GPR119 (0.49) | GPR119 | |
| SCHEMBL24265686 | 0.81 | KDM1A (0.44) | KDM1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL29574126 | 0.81 | KDM1A (0.44) | KDM1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL24265824 | 0.81 | HTR6 (0.44) | KDM1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL24265925 | 0.81 | INPPL1 (0.40) | KDM1ASLC6A2SLC6A4SLC6A3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |