Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 1/20 | 0.43 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945912 | 0.88 | KDM1A (0.39) | MAP4K3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL29946021 | 0.85 | INPPL1 (0.43) | INPPL1MAP4K3SCN9AKDM1ASIGMAR1 | |
| SCHEMBL29945954 | 0.83 | KDM1A (0.40) | MAP4K3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL29945914 | 0.81 | GPR119 (0.44) | — | |
| SCHEMBL29945894 | 0.79 | INPPL1 (0.46) | INPPL1MAP4K3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29946002 | 0.76 | HTR6 (0.49) | INPPL1MAP4K3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29945931 | 0.76 | MAP4K3 (0.50) | INPPL1MAP4K3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24265925 | 0.75 | INPPL1 (0.40) | INPPL1MAP4K3PAK1SLC6A2SLC6A4 | |
| SCHEMBL29574548 | 0.75 | INPPL1 (0.40) | INPPL1MAP4K3PAK1SLC6A2SLC6A4 | |
| SCHEMBL29946013 | 0.73 | MAP4K3 (0.39) | INPPL1MAP4K3ALKSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |