Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K3 | Q8IVH8 | 5/20 | 0.39 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
| ▸ | NPM1 | P06748 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945931 | 0.84 | MAP4K3 (0.50) | MAP4K3INPPL1SIGMAR1MCHR1 | |
| SCHEMBL29946022 | 0.78 | NR3C1 (0.44) | — | |
| SCHEMBL29945894 | 0.78 | INPPL1 (0.46) | MAP4K3INPPL1MCHR1INSRNPM1 | |
| SCHEMBL29946021 | 0.78 | INPPL1 (0.43) | MAP4K3INPPL1SIGMAR1 | |
| SCHEMBL24265554 | 0.76 | MAP4K3 (0.48) | MAP4K3SIGMAR1 | |
| SCHEMBL14635365 | 0.75 | SIGMAR1 (0.43) | SIGMAR1INSRNPM1ALKPIM1 | |
| SCHEMBL29946073 | 0.75 | MAP4K3 (0.49) | MAP4K3SIGMAR1PIM1 | |
| SCHEMBL29946008 | 0.73 | INPPL1 (0.43) | MAP4K3INPPL1SIGMAR1ALK | |
| SCHEMBL29945954 | 0.72 | KDM1A (0.40) | MAP4K3SIGMAR1ALK | |
| SCHEMBL25284217 | 0.71 | ALOX5AP (0.39) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |