Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K3 | Q8IVH8 | 6/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24265554 | 0.87 | MAP4K3 (0.48) | MAP4K3SLC6A4SLC6A2SLC6A3SIGMAR1 | |
| SCHEMBL29946073 | 0.86 | MAP4K3 (0.49) | MAP4K3HTR6SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29945954 | 0.85 | KDM1A (0.40) | MAP4K3SLC6A4SLC6A2SLC6A3SIGMAR1 | |
| SCHEMBL29946013 | 0.84 | MAP4K3 (0.39) | MAP4K3SIGMAR1INPPL1MCHR1 | |
| SCHEMBL29945894 | 0.81 | INPPL1 (0.46) | MAP4K3HTR6SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29946021 | 0.79 | INPPL1 (0.43) | MAP4K3SIGMAR1INPPL1 | |
| SCHEMBL14635365 | 0.78 | SIGMAR1 (0.43) | SIGMAR1HTR2CSRC | |
| SCHEMBL29946016 | 0.77 | GPR119 (0.46) | — | |
| SCHEMBL29946008 | 0.76 | INPPL1 (0.43) | MAP4K3SLC6A4SLC6A2SLC6A3SIGMAR1 | |
| SCHEMBL29946002 | 0.73 | HTR6 (0.49) | MAP4K3HTR6SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |