Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.45 |
| ▸ | DCK | P27707 | 7/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947269 | 0.82 | FPR2 (0.43) | FPR2PROKR1RETSCDIP6K1 | |
| SCHEMBL29947145 | 0.75 | PDE3B (0.41) | DCKRET | |
| SCHEMBL20069587 | 0.75 | FPR2 (0.58) | FPR2PROKR1RETIP6K1 | |
| SCHEMBL29947205 | 0.73 | LIPE (0.49) | — | |
| SCHEMBL29947152 | 0.73 | MCOLN2 (0.51) | FPR2PROKR1 | |
| SCHEMBL20147428 | 0.72 | FPR2 (0.53) | FPR2PROKR1RETIP6K1 | |
| SCHEMBL20158604 | 0.72 | FPR2 (0.53) | FPR2PROKR1RETSCDIP6K1 | |
| SCHEMBL16657599 | 0.69 | FPR2 (0.46) | FPR2PROKR1IP6K1CHRM3SLC6A2 | |
| Hydrochloric Acid SCHEMBL29947153 | 0.68 | FPR2 (0.46) | FPR2PROKR1IP6K1CHRM3SLC6A2 | |
| SCHEMBL29947171 | 0.68 | CHRM4 (0.46) | SCDCHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337206-A1 | HETEROCYCLIC TRPML1 AGONISTS AND USES THEREOF | Libra Therapeutics, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022240992-A1 | HETEROCYCLIC TRPML1 AGONISTS AND USES THEREOF | LIBRA THERAPEUTICS, INC. (US) | 2022-11-17 | — | — | WO | disclosed |