Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 14/20 | 0.37 |
| ▸ | JAK2 | O60674 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536235 | 0.85 | HTR6 (0.46) | JAK1JAK2 | |
| SCHEMBL23536239 | 0.85 | ALDH1A1 (0.35) | JAK1ALDH1A1KMT2A | |
| SCHEMBL29948618 | 0.79 | KMT2A (0.38) | GAAMMP2MMP3MMP9MMP8 | |
| SCHEMBL28867443 | 0.72 | SCN9A (0.38) | — | |
| SCHEMBL29931919 | 0.70 | MAPT (0.40) | GAAALDH1A1KMT2A | |
| SCHEMBL2453898 | 0.67 | KMT2A (0.39) | JAK1JAK2GAAALDH1A1GLA | |
| SCHEMBL14144348 | 0.67 | ALDH1A1 (0.54) | GAAALDH1A1KMT2A | |
| SCHEMBL5460918 | 0.66 | CYP1A2 (0.43) | JAK1JAK2ALDH1A1KMT2A | |
| SCHEMBL29650110 | 0.65 | LMNA (0.47) | GAAALDH1A1KMT2A | |
| SCHEMBL29948559 | 0.65 | CNR1 (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |