SCHEMBL29950784

SCHEMBL29950784

CCOc1cc(B(O)O)cc(C(F)(F)F)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
RXRG P48443 1/20 0.47
MGLL Q99685 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.39
MAPT P10636 2/20 0.39
LMNA P02545 2/20 0.39
ATM Q13315 1/20 0.39
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 2/20 0.36
GAA P10253 1/20 0.36
NPY1R P25929 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP1A1 P04798 2/20 0.36
CYP1B1 Q16678 2/20 0.36
PAX8 Q06710 1/20 0.36
MAOB P27338 1/20 0.36
NPSR1 Q6W5P4 2/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12260219 1.00 RXRA (0.47) RXRARXRBRXRGMGLLL3MBTL1
SCHEMBL29951977 0.87 MGLL (0.41) RXRARXRBRXRGMGLLL3MBTL1
SCHEMBL29955738 0.86 FAAH (0.42) RXRARXRBRXRGMGLLL3MBTL1
SCHEMBL3789975 0.82 NQO1 (0.44) MEN1KMT2ANQO1
SCHEMBL12128793 0.82 RXRA (0.53) RXRARXRBRXRGL3MBTL1MAPT
SCHEMBL15332805 0.81 MGLL (0.39) RXRARXRBRXRGMGLLSOD1
SCHEMBL1409616 0.81 ENPP2 (0.47) RXRARXRBRXRGMGLLL3MBTL1
SCHEMBL18770678 0.80 L3MBTL1 (0.43) RXRARXRBRXRGMGLLL3MBTL1
SCHEMBL13065645 0.78 MGLL (0.39) RXRARXRBRXRGMGLLL3MBTL1
SCHEMBL1979081 0.77 FGFR1 (0.41) L3MBTL1LMNAALDH1A1MAOBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025215450-A1 THIAZOLE COMPOUNDS AS SODIUM CHANNEL BLOCKERS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-10-16 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed