SCHEMBL29951977

SCHEMBL29951977

CCCOc1cc(B(O)O)cc(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.41
CYP1A1 P04798 2/20 0.39
CYP1B1 Q16678 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
PDK2 Q15119 1/20 0.35
FAAH O00519 2/20 0.35
LMNA P02545 2/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
ALOX12 P18054 1/20 0.35
CCR6 P51684 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
SCN9A Q15858 1/20 0.34
SOD1 P00441 1/20 0.34
GAA P10253 1/20 0.33
LTA4H P09960 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955738 0.92 FAAH (0.42) MGLLL3MBTL1RXRARXRBRXRG
SCHEMBL29950784 0.87 RXRA (0.47) MGLLCYP1A1CYP1B1L3MBTL1RXRA
SCHEMBL12260219 0.87 RXRA (0.47) MGLLCYP1A1CYP1B1L3MBTL1RXRA
SCHEMBL13481295 0.83 GPR84 (0.45) CYP1A1CYP1B1L3MBTL1RXRARXRB
SCHEMBL3790617 0.83 LTA4H (0.41) L3MBTL1LMNAMAPTLTA4H
SCHEMBL29953561 0.81 PDK2 (0.35) CYP1A1CYP1B1L3MBTL1PDK2LTA4H
SCHEMBL15332805 0.79 MGLL (0.39) MGLLRXRARXRBRXRGSCN9A
SCHEMBL17048575 0.79 CNR1 (0.45) CYP1A1CYP1B1L3MBTL1SOD1LTA4H
SCHEMBL17056171 0.78 FAAH (0.44) CYP1A1CYP1B1L3MBTL1GPR84PDK2
SCHEMBL1409616 0.78 ENPP2 (0.47) MGLLL3MBTL1RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed