Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957566 | 0.94 | HPGD (0.55) | ALDH1A3TSHRSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL29954591 | 0.85 | TSHR (0.49) | TSHRSMN1; SMN2HPGDNPSR1ALDH1A1 | |
| SCHEMBL16083180 | 0.82 | ATF4 (0.52) | TSHRSMN1; SMN2HPGDNPSR1ALDH1A1 | |
| SCHEMBL2558483 | 0.80 | ALDH1A3 (0.58) | ALDH1A3SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL29952000 | 0.80 | HPGD (0.55) | TSHRSMN1; SMN2HPGDNPSR1NPC1 | |
| SCHEMBL29956939 | 0.79 | ALDH1A1 (0.50) | TSHRSMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL29951341 | 0.79 | ALDH1A1 (0.50) | TSHRSMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL15330677 | 0.79 | HPGD (0.52) | TSHRSMN1; SMN2HPGDNPSR1ALDH1A1 | |
| SCHEMBL2557252 | 0.79 | ALDH1A3 (0.56) | ALDH1A3HPGDALDH1A1HTT | |
| SCHEMBL2556320 | 0.78 | HPGD (0.49) | TSHRHPGDALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |