Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954591 | 0.95 | TSHR (0.49) | HPGDTSHRSMN1; SMN2NPSR1POLB | |
| SCHEMBL29957566 | 0.86 | HPGD (0.55) | HPGDTSHRSMN1; SMN2NPSR1POLB | |
| SCHEMBL2560494 | 0.81 | OGG1 (0.47) | HPGDTSHRSMN1; SMN2POLBKMT2A | |
| SCHEMBL29951935 | 0.80 | ALDH1A3 (0.50) | HPGDTSHRSMN1; SMN2NPSR1RAB9A | |
| SCHEMBL2552258 | 0.80 | ALDH1A1 (0.48) | HPGDTSHRSMN1; SMN2POLBKMT2A | |
| SCHEMBL2173793 | 0.79 | SRC (0.42) | HPGDSMN1; SMN2POLBRAB9ANPC1 | |
| SCHEMBL4298184 | 0.78 | GAA (0.51) | HPGDSMN1; SMN2POLBKMT2ARAB9A | |
| SCHEMBL1409135 | 0.78 | GAA (0.51) | HPGDSMN1; SMN2POLBKMT2ARAB9A | |
| SCHEMBL2930425 | 0.78 | GAA (0.51) | HPGDSMN1; SMN2POLBKMT2ARAB9A | |
| SCHEMBL2561340 | 0.76 | OGG1 (0.48) | HPGDTSHRSMN1; SMN2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |