Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952000 | 0.95 | HPGD (0.55) | TSHRHPGDMAPTHTTMEN1 | |
| SCHEMBL29951935 | 0.85 | ALDH1A3 (0.50) | TSHRHPGDMAPTHTTALDH1A1 | |
| SCHEMBL2552258 | 0.82 | ALDH1A1 (0.48) | TSHRHPGDMAPTHTTOGG1 | |
| SCHEMBL2560494 | 0.81 | OGG1 (0.47) | TSHRHPGDMAPTHTTOGG1 | |
| SCHEMBL29957566 | 0.80 | HPGD (0.55) | TSHRHPGDALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL29951341 | 0.79 | ALDH1A1 (0.50) | TSHRHPGDMAPTALDH1A1KMT2A | |
| SCHEMBL29956939 | 0.79 | ALDH1A1 (0.50) | TSHRHPGDMAPTALDH1A1KMT2A | |
| SCHEMBL15330677 | 0.79 | HPGD (0.52) | TSHRHPGDHTTALDH1A1MEN1 | |
| SCHEMBL29950635 | 0.78 | SMN1; SMN2 (0.48) | TSHRMAPTOGG1SRCALDH1A1 | |
| SCHEMBL2561340 | 0.78 | OGG1 (0.48) | TSHRHPGDMAPTOGG1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |