SCHEMBL29952011

SCHEMBL29952011

OB(O)c1sccc1C1CCC1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
NEK2 P51955 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29958546 0.96 LMNA (0.36) LMNANEK2
SCHEMBL29954560 0.94 LMNA (0.35) LMNANEK2
SCHEMBL29956385 0.92 HSD17B10 (0.32) LMNANEK2
SCHEMBL27792331 0.68 GPR35 (0.41) LMNANEK2
SCHEMBL4458509 0.65 CEL (0.35) LMNANEK2
SCHEMBL5049851 0.65 PTGDR2 (0.34)
SCHEMBL7324741 0.65 LMNA (0.35) LMNANEK2
SCHEMBL8167373 0.65 LMNA (0.36) LMNANEK2
SCHEMBL8167370 0.65 LMNA (0.42) LMNANEK2
SCHEMBL15192199 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed