Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.33 |
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.32 |
| ▸ | CEL | P19835 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954560 | 0.98 | LMNA (0.35) | LMNANEK2CAMKK1CAMKK2CEL | |
| SCHEMBL29952011 | 0.96 | LMNA (0.33) | LMNANEK2 | |
| SCHEMBL29956385 | 0.92 | HSD17B10 (0.32) | LMNANEK2 | |
| SCHEMBL7324741 | 0.69 | LMNA (0.35) | LMNANEK2CAMKK1CAMKK2CEL | |
| SCHEMBL4458509 | 0.69 | CEL (0.35) | LMNANEK2CAMKK1CAMKK2CEL | |
| SCHEMBL8167370 | 0.69 | LMNA (0.42) | LMNANEK2CAMKK1CAMKK2 | |
| SCHEMBL4580554 | 0.68 | ALDH1A1 (0.42) | LMNACEL | |
| SCHEMBL28849763 | 0.68 | ALDH1A1 (0.42) | LMNACEL | |
| SCHEMBL5314614 | 0.68 | ESR2 (0.40) | LMNANEK2CAMKK1CAMKK2 | |
| SCHEMBL27771263 | 0.67 | ABCC1 (0.42) | LMNANEK2CAMKK1CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |