Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 10/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 10/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ATIC | P31939 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27523733 | 0.86 | HSD17B10 (0.39) | HPGDHSD17B10THRBCYP2C9TSHR | |
| SCHEMBL5766222 | 0.83 | ALDH1A1 (0.47) | HPGDHSD17B10THRBCYP2C9TSHR | |
| SCHEMBL27903036 | 0.82 | CA12 (0.44) | HPGDHSD17B10THRBCYP2C9TSHR | |
| SCHEMBL5767408 | 0.79 | KEAP1 (0.42) | HPGDHSD17B10THRBCYP2C9TSHR | |
| SCHEMBL2724263 | 0.79 | HTT (0.45) | AKR1C3AKR1C2HPGDHSD17B10THRB | |
| SCHEMBL30592903 | 0.79 | CYP1A2 (0.49) | HPGDHSD17B10THRBCYP2C9TSHR | |
| SCHEMBL1610495 | 0.79 | CYP1A2 (0.49) | HPGDHSD17B10THRBCYP2C9TSHR | |
| SCHEMBL1617941 | 0.79 | HSD17B10 (0.41) | HPGDHSD17B10THRBCYP2C9TSHR | |
| SCHEMBL11061534 | 0.79 | TP53 (0.43) | HPGDHSD17B10THRBCYP2C9TSHR | |
| SCHEMBL1041518 | 0.79 | LMNA (0.54) | HPGDHSD17B10MAPTKDM4EGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |