Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951258 | 0.86 | OPRM1 (0.46) | BCHEACHEOPRM1TMEM97SIGMAR1 | |
| SCHEMBL29951295 | 0.81 | ACHE (0.47) | BCHEACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL29954192 | 0.81 | ACHE (0.44) | BCHEACHEOPRM1TMEM97SIGMAR1 | |
| SCHEMBL14601748 | 0.81 | CYP1A2 (0.53) | SIGMAR1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29957129 | 0.80 | HTR1A (0.51) | BCHEACHETMEM97SIGMAR1MEN1 | |
| SCHEMBL1416971 | 0.79 | HTR7 (0.55) | BCHEACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL29952179 | 0.78 | CHRM2 (0.50) | BCHEACHECHRM2 | |
| SCHEMBL2556405 | 0.77 | ACHE (0.41) | BCHEACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL29950795 | 0.76 | ALDH1A1 (0.42) | SIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL29953500 | 0.75 | HTR7 (0.38) | BCHEACHEALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |