Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957129 | 0.86 | HTR1A (0.51) | ACHEBCHEMEN1ALDH1A1KMT2A | |
| SCHEMBL29954667 | 0.81 | ACHE (0.47) | ACHEBCHEMEN1ALDH1A1KMT2A | |
| SCHEMBL29952592 | 0.81 | BCHE (0.44) | ACHEBCHEMEN1ALDH1A1KMT2A | |
| SCHEMBL11659769 | 0.79 | ACHE (0.50) | ACHEALDH1A1 | |
| SCHEMBL29951579 | 0.78 | ACHE (0.47) | ACHEBCHE | |
| SCHEMBL1416971 | 0.76 | HTR7 (0.55) | ACHEBCHEMEN1ALDH1A1KMT2A | |
| SCHEMBL29950795 | 0.76 | ALDH1A1 (0.42) | MEN1ALDH1A1KMT2AHTR1AHTR2C | |
| SCHEMBL29951450 | 0.75 | GABRA1 (0.49) | MEN1ALDH1A1KMT2A | |
| SCHEMBL5991497 | 0.74 | ENPP2 (0.48) | KMT2A | |
| SCHEMBL20871857 | 0.73 | MAPT (0.54) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |