SCHEMBL29952598

SCHEMBL29952598

[C-]#[N+]c1ccc(F)cc1Br

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.34
KMT2A Q03164 1/20 0.30
CA3 P07451 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30
CA5B Q9Y2D0 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29953721 0.82 PKM (0.31) PKMCA3CA6CA5ACA9
SCHEMBL12138250 0.77 NISCH (0.33) KMT2ACA3CA6CA5ACA9
SCHEMBL29953631 0.76 ALDH1A1 (0.42) KMT2ACA3CA6CA5ACA9
SCHEMBL12136644 0.76 ALDH1A1 (0.42) KMT2ACA3CA6CA5ACA9
SCHEMBL29954159 0.76 ALOX15 (0.42) KMT2AALDH1A1CYP2A6
SCHEMBL12427234 0.74 TP53 (0.35) KMT2AALDH1A1CYP2A6
SCHEMBL29955916 0.73 CA3 (0.30) CA3CA6CA5ACA9CA14
SCHEMBL2741041 0.73 ACHE (0.35) CA3CA6CA5ACA9CA14
SCHEMBL29956971 0.73 RAB9A (0.38) KMT2AALDH1A1CYP1A2CYP2A6
SCHEMBL29956335 0.72 PTPN5 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed