SCHEMBL3038859

SCHEMBL3038859

N#Cc1c(F)ccc(B(O)O)c1F

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
TRPV4 Q9HBA0 1/20 0.33
ENPP2 Q13822 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30
TAS1R2 Q8TE23 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957667 1.00 KDM4E (0.33) KDM4ETRPV4ENPP2ALDH1A1HPGD
SCHEMBL29991689 0.84 TRPV4 (0.33) KDM4ETRPV4ENPP2ALDH1A1HPGD
SCHEMBL19924663 0.84 TRPV4 (0.33) KDM4ETRPV4ENPP2ALDH1A1HPGD
SCHEMBL25515254 0.81 L3MBTL1 (0.34) KDM4EENPP2ALDH1A1HSD17B10
SCHEMBL29170430 0.78 ENPP2 (0.40) KDM4EENPP2ALDH1A1HPGD
SCHEMBL31198326 0.78 ENPP2 (0.40) KDM4EENPP2ALDH1A1HPGD
SCHEMBL21852703 0.78
SCHEMBL29953053 0.76 KDM4E (0.44) KDM4ETRPV4ENPP2ALDH1A1HPGD
SCHEMBL4966189 0.76 KDM4E (0.44) KDM4ETRPV4ENPP2ALDH1A1HPGD
SCHEMBL186689 0.75 TRPV4 (0.42) KDM4ETRPV4ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391668-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2025-08-19 US disclosed
CN-110249031-B Organic molecules, in particular for organic optoelectronic devices 三星显示有限公司 2023-12-05 CN disclosed
US-11825743-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
EP-3585777-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2023-05-10 EP disclosed
US-20220396565-A1 NOVEL HETEROCYCLIC COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 2022-12-15 US disclosed
US-11492344-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2022-11-08 US disclosed
US-11456426-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2022-09-27 US disclosed
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-10 US disclosed
EP-3543230-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2021-05-05 EP disclosed
EP-3580300-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-10-21 EP disclosed
EP-2776396-A2 HETEROARYL HYDROXAMIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE F.HOFFMANN-LA ROCHE AG (CH) 2014-09-17 EP disclosed
US-20130102600-A1 Heteroaryl hydroxamic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease F. HOFFMANN-LA ROCHE LTD (CH) 2013-04-25 US disclosed
US-20130102601-A1 Pyrimidin-4-one derivatives and their use in the treatment, amelioration or prevention of a viral disease F. HOFFMANN-LA ROCHE LTD (CH) 2013-04-25 US disclosed
WO-2013057253-A1 PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE F. HOFFMANN-LA ROCHE AG (CH) 2013-04-25 WO disclosed
WO-2013057251-A2 HETEROARYL HYDROXAMIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE F. HOFFMANN-LA ROCHE AG (CH) 2013-04-25 WO disclosed
US-7776458-B2 Used for forming an organic layer of the organic electroluminescent device, can emit light in the wavelength range of 400-650 nm, and induce white electroluminescence when combined with green or red luminescent materials; heat resistance; highly efficient Used for forming phospholuminescence; OLEDs SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-08-17 US disclosed
US-7678473-B2 Organometallic complex and organic electroluminescent device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-03-16 US disclosed
US-7601438-B2 Cyclometalated transition metal complex and organic electroluminescent display device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2009-10-13 US disclosed
US-20060172150-A1 Organometallic complex and organic electroluminescent device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2006-08-03 US disclosed
US-20060078760-A1 Cyclometalated transition metal complex and organic electroluminescent display device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2006-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130102601-A1 Pyrimidin-4-one derivatives and their use in the treatment, amelioration or prevention of a viral disease TPMT, TYMP, HPRT1 KDM4E 3487/4885TRPV4 562/4885ENPP2 1221/4885
US-11492344-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OCIAD2, OR51E2 KDM4E 4433/4885TRPV4 374/4885ENPP2 4293/4885
US-11825743-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OCIAD2 KDM4E 4620/4885TRPV4 243/4885ENPP2 4083/4885
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, OR51E2, OCIAD2 KDM4E 4619/4885TRPV4 200/4885ENPP2 4036/4885
US-20220396565-A1 NOVEL HETEROCYCLIC COMPOUNDS MRPL21, F12, MRPS34 KDM4E 3538/4885TRPV4 2837/4885ENPP2 3226/4885
US-20060078760-A1 Cyclometalated transition metal complex and organic electroluminescent display device using the same L1CAM, PDCD2L, MAP1LC3C KDM4E 3014/4885TRPV4 444/4885ENPP2 2937/4885
US-11456426-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OCIAD2 KDM4E 4619/4885TRPV4 200/4885ENPP2 4036/4885
US-12391668-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SLC25A21, SLCO4C1, SLC18A1 KDM4E 955/4885TRPV4 74/4885ENPP2 4314/4885
US-20130102600-A1 Heteroaryl hydroxamic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease FAH, SLC10A1, OAT KDM4E 3710/4885TRPV4 3108/4885ENPP2 984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.