Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.71 |
| ▸ | MAOB | P27338 | 11/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.67 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967032 | 1.00 | MAOA (0.71) | MAOAMAOBPTGS2BCHEALOX5 | |
| SCHEMBL4803818 | 0.89 | MAOA (0.59) | MAOAMAOBPTGS2BCHEALOX5 | |
| SCHEMBL1572774 | 0.88 | MAOB (0.71) | MAOAMAOBPTGS2BCHEALOX5 | |
| SCHEMBL13004141 | 0.84 | ALDH1A1 (0.61) | MAOAMAOBPTGS2BCHEALOX5 | |
| SCHEMBL13631722 | 0.84 | MAOA (0.58) | MAOAMAOBPTGS2BCHEALOX5 | |
| SCHEMBL11876946 | 0.83 | MAPT (0.62) | MAOAMAOBPTGS2BCHEALOX5 | |
| SCHEMBL29955251 | 0.83 | MAPT (0.62) | MAOAMAOBPTGS2BCHEALOX5 | |
| SCHEMBL29956322 | 0.80 | PTPN1 (0.61) | MAOAMAOBPTGS2MAPTKDM4E | |
| SCHEMBL7372448 | 0.79 | PTPN1 (0.51) | MAOAMAOBBCHEALOX5ALOX15 | |
| SCHEMBL11565649 | 0.78 | RAB9A (0.61) | MAOAMAOBPTGS2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |