SCHEMBL29953702

SCHEMBL29953702

CCCNC(=O)CN(C)CCC=O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.38
CNR1 P21554 2/20 0.37
DNM1 Q05193 2/20 0.37
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP9 P14780 1/20 0.36
TSHR P16473 1/20 0.34
ADH1B P00325 1/20 0.33
ADH1A P07327 1/20 0.33
ADH7 P40394 1/20 0.33
ALDH1A1 P00352 1/20 0.32
EPHX1 P07099 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952363 0.86 MCL1 (0.34) MCL1ALDH1A1
SCHEMBL29955483 0.82 CNR1 (0.40) CNR1TSHRALDH1A1
SCHEMBL26838432 0.81 MCL1 (0.48) MCL1CNR1DNM1MMP1MMP2
SCHEMBL29953331 0.78 ALDH1A1 (0.33) MCL1ALDH1A1
SCHEMBL19523435 0.75 MCL1 (0.37) MCL1CNR1DNM1MMP1MMP2
SCHEMBL29955601 0.74 TSHR (0.35) TSHRALDH1A1MEN1KMT2A
SCHEMBL2127728 0.73 MCL1 (0.48) MCL1CNR1DNM1MMP1MMP2
SCHEMBL18752986 0.72 RAB9A (0.40) MCL1DNM1TSHRALDH1A1RAB9A
SCHEMBL435406 0.72 DNM1 (0.34) DNM1TSHRALDH1A1MEN1KMT2A
SCHEMBL25817161 0.71 MEN1 (0.56) DNM1TSHRALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed