SCHEMBL29953347

SCHEMBL29953347

CCCN(Cc1cc(B(O)O)ccc1OC)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.41
ACHE P22303 2/20 0.41
SIGMAR1 Q99720 2/20 0.36
ENPP2 Q13822 3/20 0.35
ALDH1A1 P00352 2/20 0.35
PKM P14618 1/20 0.34
ALOX15 P16050 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB2 P47870 2/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
APP P05067 1/20 0.33
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954950 0.83 HTR1A (0.42) BCHEENPP2ALDH1A1PKMALOX15
SCHEMBL29950795 0.78 ALDH1A1 (0.42) SIGMAR1ALDH1A1ALOX15MEN1KMT2A
SCHEMBL29951283 0.76 ALDH1A1 (0.43) ALDH1A1ALOX15
SCHEMBL18706356 0.76 ALDH1A1 (0.54) ENPP2ALDH1A1MEN1KMT2ACA1
SCHEMBL21396 0.76 ENPP2 (0.44) ENPP2ALDH1A1MEN1KMT2ACA1
SCHEMBL29951579 0.76 ACHE (0.47) BCHEACHEPKMALOX15APP
SCHEMBL29952179 0.76 CHRM2 (0.50) BCHEACHEAPP
SCHEMBL29950621 0.76 PKM (0.44) BCHEACHEENPP2ALDH1A1PKM
SCHEMBL29954150 0.76 CHRM2 (0.40) BCHEACHESIGMAR1ENPP2ALDH1A1
SCHEMBL29953032 0.75 ALDH1A1 (0.38) ENPP2ALDH1A1PKMALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed