Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957517 | 0.88 | AXL (0.38) | MAPTKIF11KDM4EMEN1KMT2A | |
| SCHEMBL29875461 | 0.80 | MAPT (0.50) | MAPTKDM4EMGLLTRPV6MAPK1 | |
| SCHEMBL1427222 | 0.80 | MAPT (0.50) | MAPTKDM4EMGLLTRPV6MAPK1 | |
| SCHEMBL29496213 | 0.77 | SLC40A1 (0.47) | KDM4EMEN1KMT2ASLC40A1HTT | |
| SCHEMBL10272166 | 0.77 | SLC40A1 (0.47) | KDM4EMEN1KMT2ASLC40A1HTT | |
| SCHEMBL15958515 | 0.74 | ALDH1A1 (0.39) | MAPTKIF11KDM4EMEN1KMT2A | |
| SCHEMBL4288 | 0.74 | ENPP2 (0.41) | MEN1KMT2AMGLLTRPV6LMNA | |
| SCHEMBL29410834 | 0.74 | ENPP2 (0.41) | MEN1KMT2AMGLLTRPV6LMNA | |
| SCHEMBL17371017 | 0.73 | MAPT (0.45) | MAPTKDM4EMGLLTRPV6MAPK1 | |
| SCHEMBL6566550 | 0.72 | IDO1 (0.59) | MAPTKIF11KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |